Isotopically Labeled Compounds
Medchemexpress LLC Cyantraniliprole-d3 | 1392493-34-3 | 99.6% | 1 MG
Cyantraniliprole-d3 is the deuterium labeled Cyantraniliprole, which is an insecticide of the ryanoid class. It is for research use only.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Exatecan-d5 mesylate | 2819276-88-3 | 99.8% | 536.58 | 1 MG
Exatecan-d5 mesylate is a deuterium-labeled version of Exatecan mesylate. It is a DNA topoisomerase I inhibitor with an IC50 of 2.2 μM (0.975 μg/mL) and is used in cancer research.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated into drug molecules, serving as tracers for quantitation during drug development.
- Deuteration has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Sphingosine-1-phosphate | 26993-30-6 | 99.5% | 379.47 | 10 MG
Sphingosine-1-phosphate (S1P) is an agonist of S1P1-5 receptors and a ligand of GPR3, GPR6, and GPR12. It functions as an intracellular second messenger and mobilizes Ca2+ as an extracellular ligand for G protein-coupled receptors. S1P is a crucial lipid mediator generated from Sphingomyelin or other membrane phospholipids and stimulates DNA synthesis, cell proliferation, and migration.
- Agonist for S1P1-5 receptors
- Ligand for GPR3, GPR6, and GPR12
- Functions as an intracellular second messenger
- Mobilizes Ca2+ as an extracellular ligand
- Crucial lipid mediator
- Stimulates DNA synthesis, cell proliferation, and migration
- High purity
- Solid appearance, white to yellow color
- For research use only
Cayman Chemical Lithocholic Acid-d4, Purity: ≥99% deuterated forms (d1-d4), CAS: 83701-16-0, 5 mg
An internal standard for the quantification of lithocholic acid by GC- or LC-MS
Medchemexpress LLC Fumaric acid-d2 | 24461-32-3 | MFCD00144378 | 99.0% | 118.08 g·mol⁻1 | C4H2D2O4 | 5 MG
Fumaric acid-d2 is the deuterium-labeled isotopologue of fumaric acid provided for laboratory research. It is used as a tracer or analytical standard in mechanistic and metabolic studies where deuterium labeling is required. The material is offered in small milligram quantities with high chemical and isotopic purity and is intended for research use only.
- High isotopic purity (99.0%).
- Chemical formula C4H2D2O4; molecular weight 118.08 g·mol⁻1.
- High solubility in DMSO (≥100 mg/mL).
- Available in small pack sizes suitable for analytical work.
- Powder storage: -20°C (up to 3 years) or 4°C (up to 2 years).
- For research use only; not for human or clinical use.
Apexbio Technology LLC Nortriptyline (hydrochloride) 894-71-3 100mg
Nortriptyline hydrochloride (CAS 894-71-3) is a dibenzocycloheptene-derived tricyclic antidepressant that inhibits monoamine reuptake transporters It selectively blocks the norepinephrine transporter (NET) with a Ki of 3 4 nM and inhibits the serotonin transporter (SERT) with a Ki of 161 nM thereby increasing synaptic concentrations of these neurotransmitters in the central nervous system In vitro nortriptyline dose-dependently suppresses spontaneous migration and chemotaxis of human polymorphonuclear cells In vivo studies in rodents indicate partial blockade of noradrenaline depletion in nerve terminals at higher doses Nortriptyline is frequently employed in research on monoaminergic neurotransmission and antidepressant pharmacology
Medchemexpress LLC Azelaic acid-d14 | 119176-67-9 | 99.86% | 5 MG
Azelaic acid-d14 is the deuterium labeled Azelaic acid. Azelaic acid is an organic compound produced by the ozonolysis of oleic acid; it is also a component of a number of hair and skin conditioners. It is for research use only and not sold to patients.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium substitution has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Sarcosine-d3 (N-methylglycine-d3) | 118685-91-9 | 99.1% | 92.11 g·mol^-1 | C3H4D3NO2 | 5 MG
Sarcosine-d3 (N-methylglycine-d3) is a deuterium-labeled analog of sarcosine provided as a high-purity analytical standard for use in mass spectrometry, tracer experiments, and quantitative studies. Supplied in small vials, the material is intended for analytical workflows that require isotopically labeled internal standards.
- Stable isotope-labeled internal standard for mass spectrometry quantification.
- High purity for reliable and reproducible analytical results.
- Available in small sizes suitable for laboratory-scale use.
- Suitable for tracer, metabolic, and quantitative studies.
- Provided as a dry material; consult the safety data sheet for storage and handling.
Cambridge Isotope Laboratories EN-1948-4 Who PCB Calibration Series (CS6) 0 2 mL
EN-1948-4 Who PCB Calibration Series (CS6) 0 2 mL
Medchemexpress LLC Palmitic acid-d31 | 39756-30-4 | 287.62 | 500 MG
Palmitic acid-d31 is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. It can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in mouse granulosa cells.
- Deuterium labeled palmitic acid.
- Long-chain saturated fatty acid.
- Commonly found in both animals and plants.
- Can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in mouse granulosa cells.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Purity: 99.56%.
- Appearance: Solid.
- Color: White to off-white.
Medchemexpress LLC L-valine-d8 | 35045-72-8 | MFCD00144704 | 99.8% | 125.20 g·mol⁻¹ | C5H3D8NO2 | 10 MG
L-Valine-d8 is the deuterated isotopologue of the essential amino acid L-valine, labeled with eight deuterium atoms and supplied for research use as a stable isotope standard or for labeled synthesis. It is commonly used as an internal standard in mass spectrometry and for metabolic and isotopic-labeling studies.
- Deuterated with eight deuterium atoms for mass-difference applications.
- High isotopic enrichment, suitable for quantitative MS analysis.
- High chemical purity for research applications.
- Available in small solid vials and solution formats for flexible use.