Isotopically Labeled Compounds
Medchemexpress LLC D-Sorbitol-d8 | 287962-59-8 | 98.9% | 5 MG
This compound is a deuterium labeled six-carbon sugar alcohol, which can be utilized as a sugar substitute. It functions as a stabilizing excipient, isotonicity agent, sweetener, humectant, thickener, and dietary supplement.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Busulfan-d8 | 116653-28-2 | 99.7% | 1 MG
Busulfan-d8 is a deuterium labeled Busulfan, functioning as a potent alkylating antineoplastic agent. It causes DNA damage by cross-linking DNAs and DNA and proteins, inhibits thioredoxin reductase, and induces apoptosis. This compound acts as an immunosuppressive and myeloablative chemotherapeutic agent.
- Deuterium labeled compound
- Functions as a potent alkylating antineoplastic agent
- Causes DNA damage by cross-linking DNAs and DNA and proteins
- Inhibits thioredoxin reductase and induces apoptosis
- Acts as an immunosuppressive and myeloablative chemotherapeutic agent
- Can be used as a tracer for quantitation during drug development
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC 4-Butylaniline-d9 | 1219794-78-1 | 158.29 | C10H6D9N | 10mg
4-Butylaniline-d9 is the deuterium labeled 4-Butylaniline[1]
![Medchemexpress LLC Thymidine-1',2',3',4',5'-13C5 | 156968-81-9 | MFCD08459922 | 99.9% | 247.19 | C10H14N2O5 ([13C]5) | 1mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000270222.png-250.jpg)
Medchemexpress LLC Thymidine-1',2',3',4',5'-13C5 | 156968-81-9 | MFCD08459922 | 99.9% | 247.19 | C10H14N2O5 ([13C]5) | 1mg
Thymidine-13C5 (DThyd-13C5 NSC 21548-13C5) is 13C-labeled Thymidine (HY-N1150)[1]
Medchemexpress LLC Acetic acid-1-13C | 1563-79-7 | MFCD00037366 | 100.0% | 61.04 | CH313CO2H | 5g
Acetic acid-1-13C is 13C labeled Acetic acid-1
Sigma Aldrich Fine Chemicals Biosciences ISOGROR-15N Powder -Growth1G
ISOGROR ISOGROR-15N Powder -Growth1G
Medchemexpress LLC Fruquintinib-d6 | 2978508-76-6 | 99.5% | 399.43 | 5 MG
Fruquintinib-d6 is the deuterium labeled Fruquintinib (HY-19912). Fruquintinib (HMPL-013) is a highly potent and selective VEGFR 1/2/3 inhibitor with IC50s of 33, 0.35, and 35 nM, respectively. It is for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 6-((6,7-Bis(methoxy-d3)quinazolin-4-yl)oxy)-N,2-dimethylbenzofuran-3-carboxamide | 2978508-76-6 | 99.5% | 399.43 | 1 MG
Fruquintinib-d6 is a deuterium-labeled analog of Fruquintinib, a selective and potent oral inhibitor of VEGFR-1, -2, and -3. This product is intended for research use only and has not been fully validated for medical applications. It is supplied as a white to off-white solid powder and should be handled by suitably qualified experienced scientists in appropriately equipped and authorized facilities. This product is classified as hazardous with several precautionary statements.
- Harmful if swallowed
- Causes skin irritation
- Causes serious eye irritation
- May cause respiratory irritation
- Stable under recommended storage conditions
Cambridge Isotope Laboratories Trifluoroacetic Acid-D (D, 99.5%), 10 G Amp, 599-00-8
Trifluoroacetic Acid-D (D, 99.5%), 10 G Amp, 599-00-8
Medchemexpress LLC Trehalose 6,6'-dimycolate (cord factor) | 61512-20-7 | MFCD18643296 | 97.0% | 2053.4 g/mol | C130H250O15 | 1 MG
Trehalose 6,6′-dimycolate is a mycobacterial cell-wall glycolipid used as a research reagent to model Mycobacterium tuberculosis-induced inflammation and granuloma formation. It modulates innate and adaptive immune responses and is applied in both in vitro and in vivo immunology studies.
- Mimics mycobacterial cord factor activity.
- Induces granuloma formation and inflammatory signaling.
- Modulates macrophage killing and antigen presentation.
- Suitable for in vitro and in vivo immunology research.
- Provided as small-quantity, high-purity material (97.0%).
Medchemexpress LLC Diphenhydramine-d6 hydrochloride | 1189986-72-8 | 99.3% | 5 MG
Diphenhydramine-d6 hydrochloride is the deuterium-labeled form of Diphenphenhydramine hydrochloride, a first-generation histamine H1-receptor antagonist with anti-cholinergic effects. It can cross the ovine blood-brain barrier (BBB). Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules primarily as tracers for quantitation during drug development. Deuteration, specifically, has gained attention for its potential to impact the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Bimatoprost-d5 | 155206-00-1 | 98.2% | 5 MG
Bimatoprost-d5 is a deuterium labeled Bimatoprost, a prostaglandin analog and a topical hypotensive agent frequently used for treating ocular hypertension and glaucoma. It also has an antiadipogenic effect.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Mephenytoin-d5 | 1185032-66-9 | 98.7% | 5 MG
Mephenytoin-d5 is a deuterium-labeled version of Mephenytoin. Mephenytoin is an anticonvulsant and acts as a substrate for CYP2C19 and CYP2B6. This compound is intended for research use only.
- This compound can be used as a tracer.
- It can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules for quantitation during the drug development process.
- Deuteration can impact the pharmacokinetic and metabolic profiles of drugs.
Sigma Aldrich Fine Chemicals Biosciences Dioctyl phthalate-3,4,5,6-d4 98 atom % D | 93952-13-7 | MFCD00144150 | 100MG
Dioctyl phthalate-3,4,5,6-d4 98 atom % D | Purity: 99% (CP) | Mol Wt: 394.58 | 93952-13-7 | MFCD00144150 | 100MG